PAL System μ-SPE Cartridges
PAL System μ-SPE Cartridges

New PAL System μSPE Cartridges

The PAL µSPE Cartridge stands for a miniaturized and robust SPE technology that allows reliable automation and reduction of used sample and solvent without compromising performance. The µSPE has therefore emerged as a new standard for extraction, purification, concentration or filtration for automated environmentally friendly analysis processes.

 

The new PAL System µSPE Cartridge consists of two parts. The polymer material used is chemically inert and free from leachables. The outer part (1) provides a higher capacity and flexible volume for filter disks (3) and the sorbent material (4). The bottom outlet is designed to penetrate pre-slit septa and to deliver directly to LC injection ports. The inner plunger (2) provides critical functionality with the compression of the sorbent/filter layers, and a precise needle guide for safe and upright transport. An essential feature is the ability to withstand high pressure and prevent leakage around the syringe needle, which allows for faster loading of larger sample volumes. Applications range from food pesticides, water, and drug analysis to forensic and pharmacological applications.

Key functionality:

  • Septumless cartridge designs with patented sealing
  • High pressure rating (up to 10 bar)
  • Multiple elutions supported
  • Sorbent capacity: up to 100 mg packing possible
  • Chemically inert materials used 
  • Free of extractables & leachables
  • Designed to penetrate pre-slit septa of vials
  • Designed to elute directly into PAL System liquid injection ports

PAL System μSPE Cartridge Selection Guide with Publications

Cartridges

Pesticides Residue Analysis

 

Application Information

 

Publications

uSPE-GCQuE1-45-V 
PAL System μSPE Cartridge
GC QuEChERS sorbent mix 1, 45 mg​
[C18, PSA, MgSO4]
108 pcs type 01-05B

 

μSPE Cartridge for GC ammenable pesticides.
Follows AOAC 2007.01 methodology.

 

Steven Lehotay et al, 2022​
https://doi.org/10.1016/j.chroma.2022.463596 

Amadeo Fernandez-Alba et al. 2023, open Access
https://doi.org/10.1016/j.chroma.2023.463906

Mette Poulson et al., 2021​, open Access
https://doi.org/10.1016/j.chroma.2021.462384

Fully Automated QuEChERS Extraction and Clean-up of Organophosphate
Pesticides in Orange Juice, Hübschmann et al, 2023

Performance Qualification Test  for PAL System µSPE GC QuEChERS-45-V  Cartridges 
 

uSPE-GCQuE2-44-V 
PAL System μSPE Cartridge
GC QuEChERS sorbent mix 2, 44 mg​
[C18, PSA, MgSO4]
108 pcs type 01-19A

 

μSPE Cartridge without Carbon for GC ammenable pesticides.
Follows AOAC 2007.01 methodology.

 

Steven Lehotay et al, 2022​
https://doi.org/10.1016/j.chroma.2022.463596 

Amadeo Fernandez-Alba et al. 2023, open Access
https://doi.org/10.1016/j.chroma.2023.463906

Mette Poulson et al., 2021​, open Access
https://doi.org/10.1016/j.chroma.2021.462384

Fully Automated QuEChERS Extraction and Clean-up of Organophosphate
Pesticides in Orange Juice, Hübschmann et al, 2023

Performance Qualification Test  for PAL System µSPE GC QuEChERS-45-V  Cartridges 

uSPE-GCQuE3-45-V
PAL System μSPE Cartridge
GC QuEChERS sorbent mix 3, 45 mg​
[PSA, MgSO4]
108 pcs type 01-14A

 

μSPE Cartridge for extraction of pesticides in general matrices.
Follows EN 15662 methodology

 

 

uSPE-LC-QuE1-30-T 
PAL System μSPE Cartridge
LC & GC QuEChERS sorbent mix, 30 mg​
[C18, Z-Sep, GCB]
96 pcs in blister type 01-03A

 

μSPE Cartridge for pesticides in complex spice matrixes

 

Goon et al: Journal of AOAC International Vol. 103, No.1, 202
https://doi.org/10.5740/jaoacint.19-0202

Performance Qualification Test  for PAL System µSPE LC QuEChERS-30-T  Cartridges 

uSPE-SAX-50-V
PAL System μSPE Cartridge
Strong Anion Exchange (SAX), 50 mg​
for polar, anionic pesticides or other anionic compounds
108 pcs type 01-20A

 

μSPE Cartridge for polar, anionic pesticides or other anionic compounds

 

Analysis of Highly Polar Pesticides  - Automated Micro-SPE Clean-up of Complex Food Matrices for LC-MS/MS
Florencia Jesús , Amadeo Rodríguez Fernández-Alba, Hans-Joachim Hübschmann

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Automated μSPE cleanup for GC/MS or LC/MS analysis of pesticides and environmental contaminants in QuEChERS extracts of foods

Walk away QuEChERS extracts clean-up

See this detailed video of the µSPE workflow for the clean-up of raw pesticides extract. The PAL µSPE Cartridge is operated in scavenger mode eluting the pesticides in a clean extract. The matrix is kept on the sorbent material. The cleaned extract can be injected without waiting time online for LC/MS or GC/MS analysis. All samples are treated on the same time axis for highest reliability.

Advantages of automated and miniaturized µ-SPE clean-up in pesticides residues analysis
Webinars

Advantages of automated and miniaturized µ-SPE clean-up in pesticides residues analysis

Recent developments in pesticides analysis extend the well-established methods to higher productivity and reliability while minimizing consumption and exposition to harmful chemicals. A workflow was developed that allows automatic preparation of calibration standards, automatic sample dilution, and automatic clean-up of sample extracts on one instrument, showing that miniaturized automated solutions are reducing errors, improving analytical consistency and protecting the environment in one convenient approach.

Presented by:

Thomi Preiswerk, Senior Account Manager, CTC Analytics AG

Gwen Lim , Specialist for automated sample preparation, CTC Analytics

Ederina Ninga, Postdoc, Research Group for Analytical Food Chemistry, Danish Technical University 

 

Automated Sample Preperation for LC-MS and GC-MS -Solutions for Food and Environmental Analysis
Webinars

Automated Sample Preperation for LC-MS and GC-MS -Solutions for Food and Environmental Analysis

In this presentation we want to discuss an important development and a demand from analytical laboratories about the standardization and the automation of sample preparation procedures for food safety, environmental, the forensic or pharmaceutical analysis.

Presented by:
Hans-Joachim Huebschmann, PhD

Fully Automated QuEChERS Extraction and µSPE Clean-up of Organophosphate Pesticides in Orange Juice
Publications

Fully Automated QuEChERS Extraction and µSPE Clean-up of Organophosphate Pesticides in Orange Juice

Chiew Mei Chong1, Hans-Joachim Hübschmann2

1 CTC Analytics Pte. Ltd., Singapore.
2 HANS Analytical Solutions, Osaka, Japan.

Routine Pesticide Analysis using Micro-SPE
Application Notes

Routine Pesticide Analysis using Micro-SPE

This report presents for the first time the application of µSPE for the clean-up of the raw extracts using ethyl acetate as extraction solvent for pesticides from different also more complex food commodities.

Analysis of Highly Polar Pesticides
Application Notes

Analysis of Highly Polar Pesticides

Micro-SPE (μSPE) emerged as an automated green micromethod for sample preparation and clean-up in food safety, proteomics, forensic, environmental and analysis since more than ten years. Applications are wideranging and cover drugs, environmental contaminants, and, in particular, the extract clean-up in multiresidue pesticide analysis. The automation of the μSPE sample preparation steps led to the desired standardization of the applied sorbent materials for extract clean-up for the large variety of food commodities, an increase in sample throughput, and the welcome potential for offline and online hyphenation with GC/MS, LC/MS or even IC analysis.

QuEChERS Compendium
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QuEChERS Compendium

Automated μSPE cleanup for GC/MS or LC/MS analysis of pesticides and environmental contaminants in QuEChERS extracts of foods

Characterization of the New PAL Micro-SPE Cartridge for Pesticides Extract Clean-up
Posters

Characterization of the New PAL Micro-SPE Cartridge for Pesticides Extract Clean-up

Since more than ten years micro-SPE (µSPE) emerged as a micromethod for sample preparation and clean-up in food safety, proteomics, forensic, environmental and analysis. Applications are wide-ranging and cover drugs, environmental contaminants, and, in particular, the QuEChERS extract cleanup in multiresidue pesticide analysis. The automation of the µSPE sample preparation steps led to the desired increase in sample throughput, unification of the used sorbent materials for food commodities, and the potential for the online hyphenation with GC/MS and LC/MS instrumentation.
 

Fully Automated QuEChERS for Organochlorine and Organophosphate Pesticides in Tomato Juice and Red Wine
Posters

Fully Automated QuEChERS for Organochlorine and Organophosphate Pesticides in Tomato Juice and Red Wine

Using PAL Robotic Tool Change (RTC) system, a fully automated QuEChERS was developed for the extraction and clean-up of organochlorine and organophosphate pesticides from homogeneous samples. The automated QuEChERS workflow includes extraction with acetonitrile, salting out with
saturated sodium chloride solution and the clean-up with PAL μSPE prior to injection into the GC-MS/MS for analysis.

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