PAL System Multiple Headspace Extraction Module

ASMS 2025 - Fully automated implementation of EPA Method 1633 for LC-MS/MS analysis of PFAS in environmental samples using a customized robotic autosampler

Widespread use and persistence of PFAS has led to ubiquitous detection in water, soil, air, and living organisms.
US EPA Method 1633 is intended for analysis of PFAS in aqueous, solid and tissue samples using LCMS/ MS at part-per-trillion concentrations.
This method involves significant sample preparation and purification steps prior to instrumental analysis, leading to bottlenecks in sample processing.
We have developed a fully automated, online μSPE-LC-MS/MS workflow based on a customized LC TriPlus RSH SMART Advanced system for high-throughput analysis of PFAS in environmental samples following EPA Method 1633 guidelines

ASMS 2025 - Fully Automated Workflow for Volatile PFAS Analysis in Food Contact Materials Using GC-Triple Quadrupole

Posters

ASMS 2025 - Fully Automated Workflow for Volatile PFAS Analysis in Food Contact Materials Using GC-Triple Quadrupole

Gas Chromatography coupled with Triple Quadrupole Mass Spectrometry (GC/TQ) offers a robust and sensitive method for
detecting volatile PFAS. However, manual sample preparation could pose a bottleneck, impacting lab productivity. This study presents a robust and fully automated method using the PAL3 platform with GC/TQ for quantifying more than 30 volatile PFAS in FCMs, such as paper coffee cups. The automation approach minimizes human error, improving reliability
and reproducibility for routine analysis and safety assessments of PFAS in FCMs.

ASMS 2025 - From Sample to Species - Automated MALDI-TOF MS Workflows for Streamlined Bacterial Identification

Posters

ASMS 2025 - From Sample to Species - Automated MALDI-TOF MS Workflows for Streamlined Bacterial Identification

Rapid and accurate bacterial identification is crucial in fields such as clinical diagnostics and food safety, yet traditional methods are often slow. MALDI-TOF MS offers apowerful alternative, but sample preparation is a bottleneck. We propose an automated workflow using a robotic platform to streamline this process. This automated MALDI-TOF MS workflow enhances bacterial identification by reducing manual steps and improvingstandardization across applications.

eBooks

Sample Preparation Compendium

Automated, Green, and Efficient
A Compendium on Micromethods in Analytical Sample Preparation

Discover robust, precise, and reliable analytical methods while following the principles of Green Analytical Chemistry in various fields such as Food & Food Safety, Environmental, Clinical, Life Science, and Chemical.

Automated Sample Prep Workflows: Save money and time

eBooks

Automated Sample Prep Workflows: Save money and time

This compendium on instrumental sample preparation showcases the many proven solutions of automated sample preparation workflows for food, environmental, pharma, life science analysis, and beyond.

Webinars

Advancing PFAS Analysis - Robotic Automation and Streamlined LC/MS Workflows

To support the scientific community and advance PFAS analysis we are proud to offer a webinar on this topic.

Key topics:

PFAS Fundamentals: Learn about the chemistry and significance of PFAS compounds.
Sample Preparation Challenges: Understand current hurdles, regulations and best practices in PFAS extraction and purification.
Automated LC/MS Workflows: Get an overview on automated workflows and see how PAL System integrates with LC/MS to optimize sample preparation and injection.
Deep Dive: Explore online SPE for PFAS analysis.

Webinars

Automated Sample Preperation for LC/MS and GC/MS - Solutions for Food and Environmental Analysis

In this presentation we want to discuss an important development and a demand from analytical laboratories about the standardization and the automation of sample preparation procedures for food safety, environmental, the forensic or pharmaceutical analysis.

Presented by:
Hans-Joachim Huebschmann, PhD

Challenges and Opportunities of Sample Preparation for Complex Matrices in Liquid Chromatography coupled with Mass Spectrometer

Webinars

Challenges and Opportunities of Sample Preparation for Complex Matrices in Liquid Chromatography coupled with Mass Spectrometer

This presentation focuses on Sample Preparation aspecting in Metabolomics and Lipidomics

Presented by:
David Ruskic and Prof. Gerard Hopfgartner, Life Sciences Mass Spectrometry, Department of Inorganic and Analytical Chemistry, University of Geneva

Automated MALDI-TOF MS Workflows for Streamlined Bacterial Identification

Application Notes

Automated MALDI-TOF MS Workflows for Streamlined Bacterial Identification

This application note demonstrates the successful automation of two sample preparation workflows, Formic Acid (FA) and Beads method, for bacterial identification using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS).

Automated Direct Derivatization and GCMS Analysis

Application Notes

Automated Direct Derivatization and GCMS Analysis

A Robust Method for Comprehensive Metabolomic Profiling of Dried Blood Spots, Serum, and Plasma

Streamlining Metabolomic Analyses with Automated Derivatization and Injection Workflows

Application Notes

Streamlining Metabolomic Analyses with Automated Derivatization and Injection Workflows

Metabolites, the dynamic molecules reflecting cellular processes, hold the potential for understanding health, disease, and
biological systems. To unlock this potential, metabolomic analyses require precise and reliable analytical methods. This App Note
explores the workflow of the Metabolomics Core Technology Platform (MCTP), a core facility of Heidelberg University (Germany),
discussing their semi-automated analysis for untargeted metabolomics and ¹³C tracing studies via gas chromatography-mass
spectrometry (GC/MS).