Food and feed analysis is a highly challenging task due to the different chemical nature and high number of analytes in complex samples. Food safety analysis follows strict governmental regulations for the control of maximum residue limits globally.
The PAL System as the industry standard front-end for GC/MS and LC/MS offers proven automated sample prep solutions. The PAL workflows for food and feed analysis follow the internationally published standard methods, often micromethods are applied for a safer green analytical chemistry.
Within the long list of monitored contaminants are pesticides using the QuECHERS extraction and micro-SPE (µSPE) cleanup for a wide range of food commodities. Also, the automated µSPE cleanup is applied for the analysis of veterinary drugs, residues of antibiotics and hormones. Highly polar pesticides like glyphosate and AMPA are analyzed using online-SPE technique on the PAL System.
For the analysis of volatile compounds like solvents or flavor compounds the PAL System offers tools for static and dynamic headspace analysis (ITEX DHS).
Solid Phase Micro Extraction technique (SPME) with SPME Fibers or the rugged SPME Arrow are used for all areas in the food industry and quality control such as beverages, meat, oils, vegetables, wine, and food contact materials.
The PAL System provides fully automated sample preparation methods for the monitoring of processing contaminations in the vegetable oil industry, analysis for adulteration by blending, or the transfer of mineral oil hydrocarbons (MOSH, MOAH).
Other important applications include the characterization of fat content, composition, nutritional value, or cis/trans-isomerism. The PAL System offers automated extraction, saponification, derivatization and online GC injection in 24/7 operation.
The steadily growing demand for food and feed analysis calls for the PAL System to provide automated solutions for high sample throughput, reproducible and error free sample preparation.
Discover our and our partners ready-to-go workflows.
Cholesterol
Complete workstation for the determination the egg content in food.
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FAMEs
Fully automated determination of fatty acid methyl estes in oils and fats.
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MCPD
Workstation for the fully automated determination of MCPD and glycidol in food
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MOSH / MOAH
Complete workstation for the determination of mineral oil contaminants in food, feed, packaging and cosmetics.
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Glyophosate
Complete workstation for the determination of glyphosate in food.
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PFAS in Drinking Water
Online SPE-LC-MS/MS Prep Solution for simple sample handling, very low solvent consumpation, and good accuracy and reproducibility.
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PAHs in foodstuff
Time saving and highly sensitive determination of PAHs
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MultiMix
Fully automated production of standards and mixes.
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Selective Ultra-Trace-Headspace Analysis
Ultra-sensitive and selective Headspace Analysis of Volatiles using ITEX - FLAVOURSPEC®
Combining this unique set-up with distinguished enrichment properties of thermal desorption by ITEX (In-tube Extraction) DHS (Dynamic Headspace) lead to a benchmark in the field of trace analysis where very lowest (sub ppb) detection limits and enhanced separation characteristics are required.
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Sterols
Fully automted determination of sterols for food control
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µSPE Clean-Up of QuEChERS extracts
The µSPE clean-up of QuEChERS extracts for the analysis of pesticides and environmental contaminations is one example of how robotic instruments can alleviate the demands of sample processing faced by researchers.
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High-Throughput Mega-Method for the Analysis of Pesticides, Veterinary Drugs, and Environmental Contaminants by UHPLCMS/ MS and Robotic Mini-SPE Cleanup + LPGC-MS/MS, Part 1: Beef
Keywords: pesticides, veterinary drugs, environmental contaminanst, QuEChERS, GC-MS, LC-MS, beef
J. Agric. Food Chem. (2020)
Quantification of allergenic plant traces in baked products by targeted proteomics using isotope marked peptides
Keywords: Allergenic food, plant allergen (soy, sesame, lupine), LC-MS/MS, quantification of allergenic plant traces, food labeling
Food Sci. Technol. (2016), 74, 286-93
Automated Mini-Column Solid-Phase Extraction Cleanup for High-Throughput Analysis of Chemical Contaminants in Foods by Low-Pressure Gas Chromatography—Tandem Mass Spectrometry
Keywords: High-throughput automation, solid-phase extraction, cleanup, pesticide residue analysis, QuEChERS sample preparation, fast GC-MS/MS, analyte protectants, environmental contaminants, foods
Chromatographia (2016) DOI:10.1007/s10337-016-3116-y
Determination of sulfur and nitrogen compounds during the processing of dry fermented sausages and their relation to amino acid generation
Keywords: Sulfur, nitrogen, volatile compound, amino acid, odor-active compound, sausage, solvent assisted flavor evaporation
Food Chem, 190 (2016) 657-664
Development of an Automated Column Solid-Phase Extraction Cleanup of QuEChERS Extracts, Using a Zirconia-Based Sorbent, for Pesticide Residue Analyses by LC-MS/MS.
Keywords: QuEChERS, micro SPE, LC-MS/MS, ITSP, µSPE, Z-Sep, zirconia, pesticide, multiresidue, avocado, citrus
J Agric Food Chem, 2015, 63(21) 5107-19
Universal Route to Polycyclic Aromatic Hydrocarbon Analysis in Foodstuff: Two-Dimensional Heart-Cut Liquid Chromatography−Gas Chromatography−Mass Spectrometry
Keywords: PAHs, polycyclic aromatic hydrocarbons, 2D LCxGC-MS, food
Anal Chem 2015 87(12):6195-203
Determination of Wine Aroma Compounds by Head Space “In tube extraction” Technique and Gas Chromatography (HS-ITEX-GC/MS)
Keywords: White wine, aroma compounds, vintage influence, ITEX, GC/MS
Bulletin UASVM Food Science and Technology 72(1) / 2015 (OPEN ACCESS)
Enantiodifferentiation of 3-sec-butyl-2-methoxypyrazine in different species using multidimensional and comprehensive two-dimensional gas chromatographic approaches.
Keywords: 3-sec-Butyl-2-methoxypyrazine, heart-cutmultidimensional gas chromatography, comprehensive two-dimensional gas chromatography, mass spectrometric detection, enantiodifferentiation
Anal. Bioanal. Chem. 2015, 407, 253-63
In-Tube Extraction-GC/MS as High Capacity Enrichment Technique for the Analysis of Alcoholic Beverages.
Keywords: ITEX, microextraction, GC/MS, volatile constituents, beer varieties
J. Agric. Food Chem. 2014, 62 (14), 3081–3091
Chemometric Discrimination of Different Tomato Cultivars Based on Their Volatile Fingerprint in Relation to Lycopene and Total Phenolics Content
Keywords: Anti-oxidant capacity, in-tube extraction ITEX, PCA, phenolic compounds, tomatoes, volatiles
Phytochem. Anal. 2014, 25 (2), 161-9
Unravelling ionization and fragmentation pathways of carotenoids using orbitrap technology: a first step towards identification of unknowns
Keywords: carotenoids, orbitrap, ionization, fragmentation, identification
J. Mass Spectrom. 2013, 48, 740-754
In-tube Extraction and GC-MS Analysis of Volatiile Components from Wild and Cultivated sea buchthorn (Hippohae rhamnoides L. ssp. Carpatica) Berry Varieties and Juice
Keywords: GC-MS, in-tube extraction ITEX, principal component analysis, volatiles, sea buckthorn fruit
Phytochem. Anal. 2013, 24, 319-328
Caffeine in Your Drink: Natural or Synthetic?
Keywords: compound-specific isotope Analysis (CSIA), high-temperature reversed-phase liquid chromatography isotope ratio mass spectrometry, HT-RPLC/IRMS
Anal. Chem. 2012, 84, 2805−2810
Automated and quantitative headspace in-tube extraction for the accurate determination of highly volatile compounds from wines and beers
Keywords: ITEX, GC, wine, beer
J. Chromatography A, 1230 (2012) 1– 7
Characterization of Novel Varietal Floral Hop Aromas by Headspace Solid Phase Microextraction and Gas Chromatography−Mass Spectrometry/Olfactometry
Keywords: SPME, GC-MS
J Agric Food Chem. 2012; 60: 12270−12281
Aroma chemical composition of red wines from different price categories and its relationship to quality.
Keywords: wine aroma compounds, odorant composition, GC/MS
J Agric Food Chem. 2012; 60:5045-56
Rapid enrichment of bioactive milk proteins and iterative, consolidated protein identification by multidimensional protein identification technology
Proteomics 2005, 5, 3836–3846
The Power of Micro Solid Phase Extraction
This eBook explores the potential of μSPE to transform analytical workflows. It highlights the key benefits of μSPE, compares it with traditional techniques and examines its application across various industries. This resource provides a comprehensive guide for scientists and lab managers looking to optimize their sample preparation processes, achieve higher precision and embrace sustainable practices in analytical chemistry.
Static and Dynamic Headspace Analysis
Advancing PFAS Analysis - Robotic Automation and Streamlined LC/MS Workflows
To support the scientific community and advance PFAS analysis we are proud to offer a webinar on this topic.
Key topics:
- PFAS Fundamentals: Learn about the chemistry and significance of PFAS compounds.
- Sample Preparation Challenges: Understand current hurdles, regulations and best practices in PFAS extraction and purification.
- Automated LC/MS Workflows: Get an overview on automated workflows and see how PAL System integrates with LC/MS to optimize sample preparation and injection.
- Deep Dive: Explore online SPE for PFAS analysis.
Solid Phase Micro Extraction (SPME) - How does it work for my samples?
This webinar offers a close insight into the operation and latest developments of automated SPME for VOCs and SVOCs by headspace, direct immersion and derivatization techniques. Key applications for food, water, environmental and forensic samples for use in every laboratory for GC/MS and LC/MS, also direct MS analysis are discussed.
Presented by:
Hans-Joachim Huebschmann, PhD
Headspace Analysis: Reproducibility of Syringe Headspace Injections for Aqueous Samples
This article describes the optimization of residual solvents analysis according USP <467> and Ph.Eur. 2.4.24 using the automated syringe headspace technique on GC-FID and GC-MS systems. The precision of analysis ranged from 4.3 to 7.8 % RSD (GC-FID) for class 2 solvents for all analytes investigated in this study. These values fully comply with USP <467> and Ph. Eur. 2.4.24 requirements.
High-Sensitivity PFAS Determination in Seafood
This application note showcases a fully automated workflow for the precise quantification of 73 PFAS in seafood. Utilizing a PAL RTC autosampler and Agilent triple quadrupole LC/MS system (LC/TQ), the method automates calibration, QuEChERS extraction, and μSPE clean-up.
PAL3 Accessories & Smart Consumables
PAL LC/MS Tools
Three new LC-MS Tools, all equipped with Smart Syringes.
Fully Automated QuEChERS Extraction and µSPE Clean-up of Organophosphate Pesticides in Orange Juice
Chiew Mei Chong1, Hans-Joachim Hübschmann2
1 CTC Analytics Pte. Ltd., Singapore.
2 HANS Analytical Solutions, Osaka, Japan.
Characterization of the New PAL micro-SPE Cartridge for Pesticides Extract Clean-up
Since more than ten years micro-SPE (µSPE) emerged as a micromethod for sample preparation and clean-up in food safety, proteomics, forensic, environmental and analysis. Applications are wide-ranging and cover drugs, environmental contaminants, and, in particular, the QuEChERS extract cleanup in multiresidue pesticide analysis. The automation of the µSPE sample preparation steps led to the desired increase in sample throughput, unification of the used sorbent materials for food commodities, and the potential for the online hyphenation with GC/MS and LC/MS instrumentation.
Fully Automated QuEChERS for Organochlorine and Organophosphate Pesticides in Tomato Juice and Red Wine
Using PAL Robotic Tool Change (RTC) system, a fully automated QuEChERS was developed for the extraction and clean-up of organochlorine and organophosphate pesticides from homogeneous samples. The automated QuEChERS workflow includes extraction with acetonitrile, salting out with
saturated sodium chloride solution and the clean-up with PAL μSPE prior to injection into the GC-MS/MS for analysis.
