Automated determination of glyphosate, AMPA and glufosinate in food by online ligand exchange SPE-LC-MS/MS
The presented method allows a time-efficient sensitive detection and quantification of glyphosate, AMPA and glufosinate in
complex food matrices by applying online SPE.
Automated Parallel Derivatization Strategy with Broad Metabolite Coverage Coupled to SWATH/MS Data Acquisition for Qualitative and Quantitative Analysis
Due to the high dynamic range of different metabolites, SWATH/MS data acqusition allows the quatification on both precursor and product ion level including flexibility of the quantifier choice.
Priming and Cleaning Instructions for 10 µL Syringes
Maintaining and preparing your syringe are two of the most important aspects to guarantee your PAL System can provide reliable results. This Article shows you the tips and tricks to adequately preapre your syringe for use as well as to prolong the lifetime.
Automated in-gel digestion on a commercial autosampler directly coupled to nanoLC-MS/MS
We have adapted a manual in-gel digestion protocol, including reduction, alkylation and acid-labile detergent assisted trypsin digestion of proteins, to be performed on a PAL RTC autosampler system.
Automated Parallel Derivatization of Metabolites
For metabolite profiling chemical derivatization has been used to improve MS sensitivity and LC retention. However, for multi-analytes quantification, the number of available isotopically labelled internal standards is limited. And, there is no single workflow which can provide large-scale metabolomics coverage in particular for polar metabolites.
Prof. Gerard Hopfgartner, Life Sciences Mass Spectrometry, Department of Inorganic and Analytical Chemistry, University of Geneva
Challenges and Opportunities of Sample Preparation for Complex Matrices in Liquid Chromatography coupled with Mass Spectrometr
This presentation focuses on Sample Preparation aspecting in Metabolomics and Lipidomics
David Ruskic and Prof. Gerard Hopfgartner, Life Sciences Mass Spectrometry, Department of Inorganic and Analytical Chemistry, University of Geneva