PAL系统为LC注射提供了无可比拟的灵活性。可以处理从nL-mL的容量。可以配置大量的注射和开关阀(高达1500巴,21800 PSI)。这使得在线SPE和复用等应用成为可能。
生命科学应用受益于专用的LC-MS工具,该工具带有气泡传感器和惰性保持回路,用于快速进样循环和主动清洗程序。
对于色谱柱复用或反冲洗操作,流量切换阀可以被整合到自动工作流程中。
Automated determination of glyphosate, AMPA and glufosinate in food by online ligand exchange SPE-LC-MS/MS
The presented method allows a time-efficient sensitive detection and quantification of glyphosate, AMPA and glufosinate in
complex food matrices by applying online SPE.
Automated Parallel Derivatization Strategy with Broad Metabolite Coverage Coupled to SWATH/MS Data Acquisition for Qualitative and Quantitative Analysis
Due to the high dynamic range of different metabolites, SWATH/MS data acqusition allows the quatification on both precursor and product ion level including flexibility of the quantifier choice.
New Tools & Options for LC-MS 2023
Speed up, Carryover down
PAL LC-MS 工具
三种新型 LC-MS 工具,均配备智能注射器。
Priming and Cleaning Instructions for 10 µL Syringes
Maintaining and preparing your syringe are two of the most important aspects to guarantee your PAL System can provide reliable results. This Article shows you the tips and tricks to adequately preapre your syringe for use as well as to prolong the lifetime.
PAL Ingenious News June 2022
Analysis of Metabolites by LC-MALDI-MS/MS
In the present work were evaluated the use of UHPLC-MALDI-MS/MS for the analysis of metabolites of talinol generated in-vitro.
Automated in-gel digestion on a commercial autosampler directly coupled to nanoLC-MS/MS
We have adapted a manual in-gel digestion protocol, including reduction, alkylation and acid-labile detergent assisted trypsin digestion of proteins, to be performed on a PAL RTC autosampler system.
PAL3 LC Tips and Hints
for PAL LC-Systems
Automated Parallel Derivatization of Metabolites
For metabolite profiling chemical derivatization has been used to improve MS sensitivity and LC retention. However, for multi-analytes quantification, the number of available isotopically labelled internal standards is limited. And, there is no single workflow which can provide large-scale metabolomics coverage in particular for polar metabolites.
Presented by:
Prof. Gerard Hopfgartner, Life Sciences Mass Spectrometry, Department of Inorganic and Analytical Chemistry, University of Geneva
Challenges and Opportunities of Sample Preparation for Complex Matrices in Liquid Chromatography coupled with Mass Spectrometr
This presentation focuses on Sample Preparation aspecting in Metabolomics and Lipidomics
Presented by:
David Ruskic and Prof. Gerard Hopfgartner, Life Sciences Mass Spectrometry, Department of Inorganic and Analytical Chemistry, University of Geneva