Challenges and Opportunities of Sample Preparation for Complex Matrices in Liquid Chromatography coupled with Mass Spectrometer
This presentation focuses on Sample Preparation aspecting in Metabolomics and Lipidomics
Presented by:
David Ruskic and Prof. Gerard Hopfgartner, Life Sciences Mass Spectrometry, Department of Inorganic and Analytical Chemistry, University of Geneva
Metabolite Profiling by Automated Methoximation and Silylation
A standardized automated workflow is suggested using a regular industry-standard x,y,z-robotic system for the individual derivatization steps at different reaction temperatures. The reagent addition, timing of the derivatization steps and analysis are controlled by the robotic system.
