微型SPE
微型SPE

固相萃取是现代实验室用于样品前处理 和净化一个参考的技术

uSPE的应用避免了被分析物的稀释,不需要溶剂蒸发或柱子干燥。典型的
应用是QuEChERS农药分析、兽药控 制、生命科学的样品过滤及更多。

在自动化样品制备工作流程中使用微型 SPE( SPE)取代了大量溶剂的手动SPE程 序,这是绿色分析化学和实验室成本节约的 重要一步。 微型SPE小柱工作时类似小的LC 柱。仅使用微量样品或洗脱溶剂。注射器作 为溶剂“泵”工作,具有恒定的流量和压 力,提供高重复性和自动化的工作流程。

传统SPE和微型SPE比较

分散性SPE

微型SPE

  • 限制的选择性,限制的净化

    • 大量的样品量和溶剂体积

    • 需要氮气蒸发

    • 最终瓶内体积大于0.5mL

  • 高选择性 尖锐的峰型

  • 无需浓缩

    • 最终体积在100-200uL (可实现在线)

    • 更好的净化效果如同LC分离

 

  • 手动操作

    • 时间消耗

    • 低样品通量

    • 批次处理

  • 无人值守的自动化

    • 小于10分钟的快速样品前处理

    • 高生产效率

    • 在色谱运行时可执行样品前处理,无需额
      外时间成本

  • 不可溯源

    • 手动前处理

    • 没有操作日志

  • 可溯源

    • 流程文档化

    • 可支持21CFR1

 

 

 

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