Analysis of Highly Polar Pesticides
Micro-SPE (μSPE) emerged as an automated green micromethod for sample preparation and clean-up in food safety, proteomics, forensic, environmental and analysis since more than ten years. Applications are wideranging and cover drugs, environmental contaminants, and, in particular, the extract clean-up in multiresidue pesticide analysis. The automation of the μSPE sample preparation steps led to the desired standardization of the applied sorbent materials for extract clean-up for the large variety of food commodities, an increase in sample throughput, and the welcome potential for offline and online hyphenation with GC-MS, LC-MS or even IC analysis.
Automated Determination of Fatty Acid Methyl Esters using a Method developed by PAL Method Composer
An efficient method for the generation and GC-analysis of FAME was generated using PAL Method Composer ver. 1.4. PAL Method Composer allows to rapidly generate methods by simple drag & drop operations.
PAL LC-MS Tools
Three new LC-MS Tools, all equipped with Smart Syringes.
Automated Sample Prep Workflows: Save money and time
This compendium on instrumental sample preparation showcases the many proven solutions of automated sample preparation workflows for food, environmental, pharma, life science analysis, and beyond.
Static and Dynamic Headspace Analysis
The PAL Compendium
PAL Ingenious News April 2021
PAL Ingenious News November 2022
Characterization of the New PAL Micro-SPE Cartridge for Pesticides Extract Clean-up
Since more than ten years micro-SPE (µSPE) emerged as a micromethod for sample preparation and clean-up in food safety, proteomics, forensic, environmental and analysis. Applications are wide-ranging and cover drugs, environmental contaminants, and, in particular, the QuEChERS extract cleanup in multiresidue pesticide analysis. The automation of the µSPE sample preparation steps led to the desired increase in sample throughput, unification of the used sorbent materials for food commodities, and the potential for the online hyphenation with GC-MS and LC-MS instrumentation.
Untargeted 2DxLC-Mass Spectrometry using SWATH-DIA-Based Workflow for the Characterization of Lipid Profiles in Plasma Samples
The use of lipidomic analyses based on LC-mass spectrometry has become widespread due to its sensitivity and specificity which provides a broader picture of lipid profiles in biofluids. In this work, we combined an automated sample extraction and a two-dimensional liquid chromatography (2DxLC) system with HILIC-based class separation followed by an orthogonal reverse-phase chromatography with an untargeted SWATH-DIA workflow to accurately annotate phosphatidylcholines (PC), lysophosphatidylcholine (LPC) and etherphosphatidylcholines (PC O-) in human plasma samples.
Advantages of automated and miniaturized µ-SPE clean-up in pesticides residues analysis
Recent developments in pesticides analysis extend the well-established methods to higher productivity and reliability while minimizing consumption and exposition to harmful chemicals. A workflow was developed that allows automatic preparation of calibration standards, automatic sample dilution, and automatic clean-up of sample extracts on one instrument, showing that miniaturized automated solutions are reducing errors, improving analytical consistency and protecting the environment in one convenient approach.
Presented by:
Thomi Preiswerk, Senior Account Manager, CTC Analytics AG
Gwen Lim , Specialist for automated sample preparation, CTC Analytics
Ederina Ninga, Postdoc, Research Group for Analytical Food Chemistry, Danish Technical University
Solid phase microextraction (SPME) - How does it work for my samples?
This webinar offers a close insight into the operation and latest developments of automated SPME for VOCs and SVOCs by headspace, direct immersion and derivatization techniques. Key applications for food, water, environmental and forensic samples for use in every laboratory for GC-MS and LC-MS, also direct MS analysis are discussed.
Presented by:
Hans-Joachim Huebschmann, PhD
