Automated Calibration Curve Preparation - Introducing the PAL Pipette Tool with Liquid Level Detection and Fliptube Manipulation
Pipetting is the "workstation" of the analytical laboratory - a fundamental task that, despite its routine nature, remains a significant source of the "known unknown": operator variability. In this study, we evaluate the newly launched PAL Pipette Tool LLD FT, the next-generation of the reliable PAL Pipette Tool.
ASMS 2025 - Fully Automated Workflow for Volatile PFAS Analysis in Food Contact Materials Using GC-Triple Quadrupole
Gas Chromatography coupled with Triple Quadrupole Mass Spectrometry (GC/TQ) offers a robust and sensitive method for
detecting volatile PFAS. However, manual sample preparation could pose a bottleneck, impacting lab productivity. This study presents a robust and fully automated method using the PAL3 platform with GC/TQ for quantifying more than 30 volatile PFAS in FCMs, such as paper coffee cups. The automation approach minimizes human error, improving reliability
and reproducibility for routine analysis and safety assessments of PFAS in FCMs.
Automated Parallel Derivatization of Metabolites
For metabolite profiling chemical derivatization has been used to improve MS sensitivity and LC retention. However, for multi-analytes quantification, the number of available isotopically labelled internal standards is limited. And, there is no single workflow which can provide large-scale metabolomics coverage in particular for polar metabolites.
Presented by:
Prof. Gerard Hopfgartner, Life Sciences Mass Spectrometry, Department of Inorganic and Analytical Chemistry, University of Geneva
