衍生反应是许多色谱方法中经典的样品制备步骤。人工衍生通常需要几个处理步骤，通常涉及危险试剂。PAL System在分析前以提前样品准备模式
提供实时衍生，为大样本系列提供最佳再现性，尤其是代谢组学分析所需的再现性。
Figure 1: Directed evolution of a genetically encoded immobilized lipase for the efficient production of biodiesel from waste cooking oil
Author: Bradley S. Heater et al
Publication: Biotechnology for Biofuels & Bioproducts
Publisher: Springer Nature
Date: Jun 28, 2019 (http://creativecommons.org/licenses/by/4.0/)
ASMS 2025 - Automating Sample Preparation for High-Throughput Metabolomic Profiling. Using the MxP® Quant 500 kit and TriPlus RSH Autosampler
The analysis of small molecules and lipids in blood offers insights into systemic physiological and pathological states. Accurate metabolite quantification is essential to detect metabolic alterations associated with health, nutrition anddisease status and therapeutic interventions, underpinning biomarker discovery and precision medicine. Achieving reliable and consistent metabolite quantification in complex biofluids such as blood serum and plasma requires standardized sample handling and analytical workflows.
Automated Workflow for the determintation of Fatty Acid Methyl Esters (FAME)
This work presents a fully automated workflow using a workstation with robotic tool change (RTC based on a method using sodium methoxide in methanol as reactant .The workflow improves process safety, optimizes throughput and minimizes handling error.
Sample Preparation Compendium
Automated, Green, and Efficient
A Compendium on Micromethods in Analytical Sample Preparation
Discover robust, precise, and reliable analytical methods while following the principles of Green Analytical Chemistry in various fields such as Food & Food Safety, Environmental, Clinical, Life Science, and Chemical.
Automated Parallel Derivatization of Metabolites
For metabolite profiling chemical derivatization has been used to improve MS sensitivity and LC retention. However, for multi-analytes quantification, the number of available isotopically labelled internal standards is limited. And, there is no single workflow which can provide large-scale metabolomics coverage in particular for polar metabolites.
Presented by:
Prof. Gerard Hopfgartner, Life Sciences Mass Spectrometry, Department of Inorganic and Analytical Chemistry, University of Geneva
Automated Sample Preperation for LC/MS and GC/MS - Solutions for Food and Environmental Analysis
In this presentation we want to discuss an important development and a demand from analytical laboratories about the standardization and the automation of sample preparation procedures for food safety, environmental, the forensic or pharmaceutical analysis.
Presented by:
Hans-Joachim Huebschmann, PhD
Automated Determination of Fatty Acid Methyl Esters using a Method developed by PAL Method Composer
An efficient method for the generation and GC-analysis of FAME was generated using PAL Method Composer ver. 1.4. PAL Method Composer allows to rapidly generate methods by simple drag & drop operations.
