SPME是一种真正的无溶剂和绿色分析技术，也是一种非常有效的自
动化样品制备方法。它用于将基质（固体、液体或气体）中的有机物
萃取到Fiber的固定相中。分析物在气相色谱仪的进样口中直接热解
吸。最初主要用于从水性基质中提取具有优异灵敏度的溶剂，如今的
应用范围从化学、环境到医疗应用。
关于SPME Fibers的规格和操作的详细信息已经可用
(1) Detection of substituted benzenes in water at the pg/ml level using solid-phase microextraction and gas chromatography-ion trap mass spectrometry.
Potter DW, Pawliszyn J.
J Chromatogr. 1992 Nov 20;625(2):247-55.
GC/MS determination of stale aldehydes in beer by SPME on-fibre derivatization
The obvious advantage of the SPME/GC-MS method to analyze stale aldehydes in beer gives a rapid extraction and better separation with small sample volumes. It is a very suitable solution for the monitoring of the status of beer aging and keep it as its best quality.
Enhanced Method Development Capabilities with Automated SPME Extraction Optimization
A workflow is described that enables the automated selection of the most suitable extraction conditions (type of fiber, extraction time and temperature) for the GC/MS analysis of a number of contaminants in oil and water samples.
