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Micromethods - Automated µSPE Cleanup for High-Throughput QuEChERS Analysis

Micromethods - Automated µSPE Cleanup for High-Throughput QuEChERS Analysis

If you're looking for ways to improve your analysis of complex matrices or trace contaminants, these expert-led sessions are for you

Tired of manual uSPE? See how a fully automated, miniaturized µSPE workflow provides a superior cleanup for tough matrices like fats, oils, and spices, helping you reduce instrument maintenance and improve reproducibility.

Micromethods - Modern SPME Geometries - A Focus on Volatile PFAS Analysis

Webinars

Micromethods - Modern SPME Geometries - A Focus on Volatile PFAS Analysis

If you're looking for ways to improve your analysis of complex matrices or trace contaminants, these expert-led sessions are for you

Join us for a deep dive into recent research comparing SPME Fiber and SPME Arrow for ultra-trace volatile PFAS. Learn directly from the author which geometry and extraction mode provides the best performance.

Webinars

Advancing PFAS Analysis - Robotic Automation and Streamlined LC/MS Workflows

To support the scientific community and advance PFAS analysis we are proud to offer a webinar on this topic.

Key topics:

PFAS Fundamentals: Learn about the chemistry and significance of PFAS compounds.
Sample Preparation Challenges: Understand current hurdles, regulations and best practices in PFAS extraction and purification.
Automated LC/MS Workflows: Get an overview on automated workflows and see how PAL System integrates with LC/MS to optimize sample preparation and injection.
Deep Dive: Explore online SPE for PFAS analysis.

Optimizing the Preconcentration of Volatile PFAS Precursors - A Comparative Study of SPME Geometries

Application Notes

Optimizing the Preconcentration of Volatile PFAS Precursors - A Comparative Study of SPME Geometries

This Application Note summarizes a study by Williams et al. (2025) that performs a comprehensive comparison of two Solid Phase Microextraction (SPME) geometries: the traditional SPME Fiber and the robust SPME Arrow. The study systematically evaluates the impact of SPME geometry and extraction mode (Headspace vs. Direct Immersion) on extraction efficiency. The results provide a clear, data-driven basis for method development, showing how SPME configurations can be optimized for the specific physicochemical properties of different PFAS analytes.

Application Notes

Tackling Forever Chemicals

A Fully Automated Workflow for High-Throughput Analysis of Volatile PFAS in Food Contact Materials.

Webinars

Webinar Series on Automated PFAS Analysis

Forever chemicals, forever challenges?

The world of PFAS analysis is demanding, with tightening regulations and complex sample matrices pushing laboratories to their limits. This complimentary webinar series cuts through the noise, offering practical, expert-led guidance on how automated sample preparation can transform your workflows. Explore our webinars to learn how to boost sensitivity, ensure reproducibility, and tame the forever chemicals for good. We will touch on different sample workflows as well as spotlight different matrices, from food & food safety to environmental sample types.

PFAS in Cosmetics -A Comparative Analysis of Sample Preparation Techniques for PFAS Analysis

Application Notes

PFAS in Cosmetics -A Comparative Analysis of Sample Preparation Techniques for PFAS Analysis

This application note explores a comparative study that tackles this challenge head-on by evaluating two powerful sample preparation techniques: Solid Phase Microextraction (SPME) and Micro Solid Phase Extraction (µSPE) for analyzing eight key PFAS in mascara by Liquid Chromatography with Mass Spectrometry (LC/MS). The investigation revealed that the two methods offer complementary strengths. SPME proved more sensitive for water-soluble PFAS and offered a simpler, filtration-free workflow. In contrast, automated µSPE excelled for oil-soluble PFAS but required a sample filtration step.

Automated SPME-SICRIT-MS for Rapid Screening of Contaminants in Food and Environmental Matrices

Application Notes

Automated SPME-SICRIT-MS for Rapid Screening of Contaminants in Food and Environmental Matrices

Ambient mass spectrometry offers a path to rapid, direct analysis with minimal sample preparation. This note describes a high-throughput workflow for the analysis of both polar and non-polar analytes by coupling automated Solid Phase Microextraction (SPME) with soft ionization by chemical reaction in transfer (SICRIT), a variant of dielectric barrier discharge ionization (DBDI).
Using a PAL RTC autosampler, this workflow enables the rapid screening of contaminants in various water, soil, and food matrices.

ASMS 2025 - Streamlined Analysis of Polar and Non-Polar Metabolites in Plasma Using Automated Micro-SPE LC/MS

Posters

ASMS 2025 - Streamlined Analysis of Polar and Non-Polar Metabolites in Plasma Using Automated Micro-SPE LC/MS

This poster presents two use cases for streamlined lipid profiling in plasma using automated Micro Solid Phase Extraction (μSPE). Where the workflows on NIST (SRM 1950) plasma samples was tested, with spiked internal standard (Ultimate SPLASH ONE) and optimized the extraction and elution parameters. Briefly, it focused on two cartridge sorbent types Mixed-Mode Cation Exchange (MCX) and C18 (CEC) and showcased their usage.

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