LC Liquid Injection
LC Liquid Injection

LC injections, precise and with short cycle times.

The PAL System offers unrivalled flexibility for LC injections. Volumes from nL-mL can be handled. A large variety of injection and switching valves (up to 1500 bar, 21800 PSI) can be configured. This allows applications like online SPE and multiplexing.

precise LC injections

  • LC injections are performed on the PAL System by using syringes, the LC/MS tool, pipette tools or directly from µSPE cartridges.

  • The PAL System injects precisely into HPLC, UPLC or nano LC systems. Sample loops can be operated in filled-loop or partial-loop mode. Injection volumes range from 500 nL to 10 mL.

LCMS pump

  • Life science applications benefit from the dedicated LC/MS tool with bubble sensor and inert holding loop for fast injection cycles with active wash procedure. 

  • For column multiplexing or backflush operation flow switching valves can be integrated into the automated workflows.

Related Content

Automated determination of glyphosate, AMPA and glufosinate in food by online ligand exchange SPE-LC-MS/MS
Application Notes

Automated determination of glyphosate, AMPA and glufosinate in food by online ligand exchange SPE-LC-MS/MS

The presented method allows a time-efficient sensitive detection and quantification of glyphosate, AMPA and glufosinate in
complex food matrices by applying online SPE.

Read more
Automated Parallel Derivatization Strategy with Broad Metabolite Coverage Coupled to SWATH/MS Data Acquisition for Qualitative and Quantitative Analysis
Application Notes

Automated Parallel Derivatization Strategy with Broad Metabolite Coverage Coupled to SWATH/MS Data Acquisition for Qualitative and Quantitative Analysis

 Due to the high dynamic range of different metabolites, SWATH/MS data acqusition allows the quatification on both precursor and product ion level including flexibility of the quantifier choice.
 

Read more
New Tools & Options for LC-MS
Brochures

New Tools & Options for LC-MS

Speed up, Carryover down

Read more
PAL LC-MS Tools
Brochures

PAL LC-MS Tools

Three new LC-MS Tools, all equipped with Smart Syringes.

Read more
Priming and Cleaning Instructions for 10 µL Syringes
Care & User (handling) Guides

Priming and Cleaning Instructions for 10 µL Syringes

Maintaining and preparing your syringe are two of the most important aspects to guarantee your PAL System can provide reliable results. This Article shows you the tips and tricks to adequately preapre your syringe for use as well as to prolong the lifetime.

 

 

Read more
PAL Ingenious News June 2022
PAL Ingenious News

PAL Ingenious News June 2022

  • Bispecific Antibody Clone Selection
  • New Tools for LC-MS
  • New Tools for LC-MS Sample Prep
  • Tray Cooler: One for all samples
Read more
Analysis of Metabolites by LC-MALDI-MS/MS
Posters

Analysis of Metabolites by LC-MALDI-MS/MS

In the present work were evaluated the use of UHPLC-MALDI-MS/MS for the analysis of metabolites of talinol generated in-vitro.

Read more
Automated in-gel digestion on a commercial autosampler directly coupled to nanoLC-MS/MS
Posters

Automated in-gel digestion on a commercial autosampler directly coupled to nanoLC-MS/MS

We have adapted a manual in-gel digestion protocol, including reduction, alkylation and acid-labile detergent assisted trypsin digestion of proteins, to be performed on a PAL RTC autosampler system.

Read more
PAL3 LC Tips and Hints
Technical Information / Specifications

PAL3 LC Tips and Hints

for PAL LC-Systems

Read more
Automated Parallel Derivatization of Metabolites
Webinars

Automated Parallel Derivatization of Metabolites

For metabolite profiling chemical derivatization has been used to improve MS sensitivity and LC retention. However, for multi-analytes quantification, the number of available isotopically labelled internal standards is limited. And, there is no single workflow which can provide large-scale metabolomics coverage in particular for polar metabolites.

Presented by:
Prof. Gerard Hopfgartner, Life Sciences Mass Spectrometry, Department of Inorganic and Analytical Chemistry, University of Geneva

Read more
Challenges and Opportunities of Sample Preparation for Complex Matrices in Liquid Chromatography coupled with Mass Spectrometer
Webinars

Challenges and Opportunities of Sample Preparation for Complex Matrices in Liquid Chromatography coupled with Mass Spectrometer

This presentation focuses on Sample Preparation aspecting in Metabolomics and Lipidomics

Presented by:
David Ruskic and Prof. Gerard Hopfgartner, Life Sciences Mass Spectrometry, Department of Inorganic and Analytical Chemistry, University of Geneva

Read more
Contact Jobs LinkedIn
Contact Jobs LinkedIn