Liquid/liquid extractions
Liquid/liquid extractions

Fully Automated Liquid Extraction

Liquid/liquid extractions (LLE) but also solid/liquid extractions (SLE) are widely used sample pre-preparation methods in analytical laboratories.

Liquid/Liquid and Solid/Liquid Extractions
  • Typical examples are the analysis of wastewater with immiscible solvents. Very well-known is the QuEChERS pesticide extraction with acetonitrile, or the FAMEs analysis with prior heptane extraction of the lipids. A dispenser module and solvent reservoirs are used to provide the required solvent amount to the sample. 

  • The PAL System uniquely allows LLE as a micromethod from 2 mL vials, but also handles vial sizes up to 40 mL in a Vortex unit. A centrifugation step may be required to separate particles or facilitate phase separation. 

  • Any kind of organic solvent can be used. The unique bottom sensing of the PAL System allows precise aspiration of heavy extraction solvents from the vial bottom. In micromethods tapered vial types are preferred.

Related Content

Automated Sample Preperation for LC-MS and GC-MS -Solutions for Food and Environmental Analysis
Webinars

Automated Sample Preperation for LC-MS and GC-MS -Solutions for Food and Environmental Analysis

In this presentation we want to discuss an important development and a demand from analytical laboratories about the standardization and the automation of sample preparation procedures for food safety, environmental, the forensic or pharmaceutical analysis.

Presented by:
Hans-Joachim Huebschmann, PhD

Read more
Challenges and Opportunities of Sample Preparation for Complex Matrices in Liquid Chromatography coupled with Mass Spectrometer
Webinars

Challenges and Opportunities of Sample Preparation for Complex Matrices in Liquid Chromatography coupled with Mass Spectrometer

This presentation focuses on Sample Preparation aspecting in Metabolomics and Lipidomics

Presented by:
David Ruskic and Prof. Gerard Hopfgartner, Life Sciences Mass Spectrometry, Department of Inorganic and Analytical Chemistry, University of Geneva

Read more
PFAS LCMS
Flyer

PFAS LCMS

Discover how to automate your PFAS Analysis

Read more
Determination of iodoform in drinking water by PAL SPME Arrow and GC/MS
Application Notes

Determination of iodoform in drinking water by PAL SPME Arrow and GC/MS

Here we describe the quantitative analysis of iodoform in tap water by PAL SPME Arrow extraction combined with GC/MS. Immersion as well as headspace SPME has been performed on two different fiber types. The PAL SPME Arrow is a new technology for microextraction, combining trace level sensitivity with high mechanical robustness.

Read more
Fully Automated Liquid-Liquid Extraction and Headspace Extraction for the Analysis of Nitrosamine Impurities in Drug Products
Application Notes

Fully Automated Liquid-Liquid Extraction and Headspace Extraction for the Analysis of Nitrosamine Impurities in Drug Products

A completely automated Nitrosamine extraction method as per specified by FDA for Direct Injection and Headspace can be performed on the same PAL RTC.

Read more
PAL3 Accessories & Smart Consumables
Brochures

PAL3 Accessories & Smart Consumables

Discover our Toolbox

Read more
Priming and Cleaning Instructions for 10 µL Syringes
Care & User (handling) Guides

Priming and Cleaning Instructions for 10 µL Syringes

Maintaining and preparing your syringe are two of the most important aspects to guarantee your PAL System can provide reliable results. This Article shows you the tips and tricks to adequately preapre your syringe for use as well as to prolong the lifetime.

 

 

Read more
Contact Jobs LinkedIn