SPME Fibers - Excellent extraction properties

Optimizing the Preconcentration of Volatile PFAS Precursors - A Comparative Study of SPME Geometries

Optimizing the Preconcentration of Volatile PFAS Precursors - A Comparative Study of SPME Geometries

This Application Note summarizes a study by Williams et al. (2025) that performs a comprehensive comparison of two Solid Phase Microextraction (SPME) geometries: the traditional SPME Fiber and the robust SPME Arrow. The study systematically evaluates the impact of SPME geometry and extraction mode (Headspace vs. Direct Immersion) on extraction efficiency. The results provide a clear, data-driven basis for method development, showing how SPME configurations can be optimized for the specific physicochemical properties of different PFAS analytes.

PFAS in Cosmetics -A Comparative Analysis of Sample Preparation Techniques for PFAS Analysis

Application Notes

PFAS in Cosmetics -A Comparative Analysis of Sample Preparation Techniques for PFAS Analysis

This application note explores a comparative study that tackles this challenge head-on by evaluating two powerful sample preparation techniques: Solid Phase Microextraction (SPME) and Micro Solid Phase Extraction (µSPE) for analyzing eight key PFAS in mascara by Liquid Chromatography with Mass Spectrometry (LC/MS). The investigation revealed that the two methods offer complementary strengths. SPME proved more sensitive for water-soluble PFAS and offered a simpler, filtration-free workflow. In contrast, automated µSPE excelled for oil-soluble PFAS but required a sample filtration step.

Enhanced Method Development Capabilities with Automated SPME Extraction Optimization

Posters

Enhanced Method Development Capabilities with Automated SPME Extraction Optimization

A workflow is described that enables the automated selection of the most suitable extraction conditions (type of fiber, extraction time and temperature) for the GC/MS analysis of a number of contaminants in oil and water samples.

Webinars

Solid Phase Microextraction (SPME) - How does it work for my samples?

This webinar offers a close insight into the operation and latest developments of automated SPME for VOCs and SVOCs by headspace, direct immersion and derivatization techniques. Key applications for food, water, environmental and forensic samples for use in every laboratory for GC/MS and LC/MS, also direct MS analysis are discussed.

Presented by:
Hans-Joachim Huebschmann, PhD

Flavor and Off-Flavour Analysis using Solid Phase Extraction webinar

Webinars

Flavor and Off-Flavor Analysis using Solid Phase Microextraction

Solid Phase Micro Extraction (SPME) is widely used for chemical analysis of foods, beverages and food contact materials. As an automated technique, the SPME applications are selected for their simplicity, throughput and extraction efficiency. As a solvent-free extraction, it is gains even more importance today as a green analytic technique. Besides the traditional SPME Fiber, the new SPME Arrow is enhancing trace level sensitivity at high mechanical robustness. With these features, this presentation will give insight on SPME analysis in coffee, wine and off-flavors.

Presented by:

Erich Leitner, Graz University of Technology Institute of Analytical Chemistry and Food Chemistry

Stefan Cretnik, PhD, Product Manager, CTC Analytics AG

eBooks

Sample Preparation Compendium

Automated, Green, and Efficient
A Compendium on Micromethods in Analytical Sample Preparation

Discover robust, precise, and reliable analytical methods while following the principles of Green Analytical Chemistry in various fields such as Food & Food Safety, Environmental, Clinical, Life Science, and Chemical.