LC liquid injections - with minimized carryover operated by PAL System

Analysis of Metabolites by LC-MALDI-MS/MS

In the present work were evaluated the use of UHPLC-MALDI-MS/MS for the analysis of metabolites of talinol generated in-vitro.

Automated in-gel digestion on a commercial autosampler directly coupled to nano LC-MS/MS

Posters

Automated in-gel digestion on a commercial autosampler directly coupled to nano LC-MS/MS

We have adapted a manual in-gel digestion protocol, including reduction, alkylation and acid-labile detergent assisted trypsin digestion of proteins, to be performed on a PAL RTC autosampler system.

eBooks

Sample Preparation Compendium

Automated, Green, and Efficient
A Compendium on Micromethods in Analytical Sample Preparation

Discover robust, precise, and reliable analytical methods while following the principles of Green Analytical Chemistry in various fields such as Food & Food Safety, Environmental, Clinical, Life Science, and Chemical.

Metabolomics Spotlight Talk Gerard Hopfgartner

Webinars

Automated Parallel Derivatization of Metabolites

For metabolite profiling chemical derivatization has been used to improve MS sensitivity and LC retention. However, for multi-analytes quantification, the number of available isotopically labelled internal standards is limited. And, there is no single workflow which can provide large-scale metabolomics coverage in particular for polar metabolites.

Presented by:
Prof. Gerard Hopfgartner, Life Sciences Mass Spectrometry, Department of Inorganic and Analytical Chemistry, University of Geneva

Challenges and Opportunities of Sample Preparation for Complex Matrices in Liquid Chromatography coupled with Mass Spectrometer

Webinars

Challenges and Opportunities of Sample Preparation for Complex Matrices in Liquid Chromatography coupled with Mass Spectrometer

This presentation focuses on Sample Preparation aspecting in Metabolomics and Lipidomics

Presented by:
David Ruskic and Prof. Gerard Hopfgartner, Life Sciences Mass Spectrometry, Department of Inorganic and Analytical Chemistry, University of Geneva

Automated determination of glyphosate, AMPA and glufosinate in food by online ligand exchange SPE-LC-MS/MS

Application Notes

Automated determination of glyphosate, AMPA and glufosinate in food by online ligand exchange SPE-LC-MS/MS

The presented method allows a time-efficient sensitive detection and quantification of glyphosate, AMPA and glufosinate in
complex food matrices by applying online SPE.

Automated Parallel Derivatization Strategy with Broad Metabolite Coverage Coupled to SWATH/MS Data Acquisition for Qualitative and Quantitative Analysis

Application Notes

Automated Parallel Derivatization Strategy with Broad Metabolite Coverage Coupled to SWATH/MS Data Acquisition for Qualitative and Quantitative Analysis

Due to the high dynamic range of different metabolites, SWATH/MS data acqusition allows the quatification on both precursor and product ion level including flexibility of the quantifier choice.

How to use PAL Method Composer

Flyer

PFAS LCMS

Discover how to automate your PFAS Analysis

Brochures

Minimize PFAS Background with PAL System Upgrade Kits

Equip your PAL Systems for PFAS Analysis with Upgrade Kits and minimize PFAS Background.

Brochures

New Volumetric Pump Enhances LC/MS Injection Efficiency

Speed up, Carryover down

Smart Syringe being mounted in PAL Liquid Tool

Care & User (handling) Guides

Priming and Cleaning Instructions for 10 µl Syringes

Maintaining and preparing your syringe are two of the most important aspects to guarantee your PAL System can provide reliable results. This Article shows you the tips and tricks to adequately preapre your syringe for use as well as to prolong the lifetime.